Tiredness on Primo E

JuiceTrain

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Correct me if I'm wrong but seems like the only thing I should really worry about is TSH & LDL...

Maybe a T3/T4 supplement to increase levels a bit, idk if that's the reason I get frequent cravings for "junk" foods

& LDL is subsequently raised because of satisfying those cravings...



- Current Doses are 300 Cyp // 200 Deca
 

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Forgot to get CBC/CMP,
So guess who's gettin' jabbed again today...
 

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Correct me if I'm wrong but seems like the only thing I should really worry about is TSH & LDL...

Maybe a T3/T4 supplement to increase levels a bit, idk if that's the reason I get frequent cravings for "junk" foods

& LDL is subsequently raised because of satisfying those cravings...



- Current Doses are 300 Cyp // 200 Deca
Cholesterol can be fixed, stop eating so much junk 😅.

Do not take t3/t4. If your TSH is too low then there's a good chance that you're producing too much T3/T4. You need a full thyroid panel to truly understand what's happening.
 

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Cholesterol can be fixed, stop eating so much junk 😅.

Do not take t3/t4. If your TSH is too low then there's a good chance that you're producing too much T3/T4. You need a full thyroid panel to truly understand what's happening.
@JuiceTrain also, you're pretty close to 0.5 on TSH, which is typically the bottom of what most doctors consider acceptable range. It doesn't necessarily mean anything is or isn't wrong.

This is why you need a full thyroid panel.

If you're doing this through a doctor then ask if it's anything to be concerned about. If he says yes then ask if they can get you a full panel, and then post up the results.

If you're ordering the lab work yourself, then just order a full thyroid panel. Again, post up the results.
 

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@JuiceTrain also, you're pretty close to 0.5 on TSH, which is typically the bottom of what most doctors consider acceptable range. It doesn't necessarily mean anything is or isn't wrong.

This is why you need a full thyroid panel.

If you're doing this through a doctor then ask if it's anything to be concerned about. If he says yes then ask if they can get you a full panel, and then post up the results.

If you're ordering the lab work yourself, then just order a full thyroid panel. Again, post up the results.

Gotcha,
I'm going through Defy but had to get those last 2test before speaking to one of their docs...I'll ask em when I get the chance

Thanks for the info Send🤙🏾
 

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Gotcha,
I'm going through Defy but had to get those last 2test before speaking to one of their docs...I'll ask em when I get the chance

Thanks for the info Send🤙🏾
Are you sweating more, feeling anxious, getting palpitations, sweating more, have any amount of insomnia, or anything out of the ordinary besides feeling tired?

If not then you're probably actually fine. Despite how the range looks, it seems that a lot of clinics say anything below 2.5 - 3.0 is optimal.

This document from the endocrine society compares a number of studies, studies referenced in that document also suggest or imply that below 2.5 - 3.0 is optimal for long term health. Several of the studies looked at healthy men in their 20's, and only ~10-12% had levels above 3.0. Those same studies saw tsh increase with age in their test groups.


I double checked what I said earlier about the lower range doctors like, and it seems that the lower level guidelines for TSH have been updated, I said 0.5 but it's changed to 0.4. So being nearly 0.5 wouldn't concern me as long as there are no other symptoms present.

As always, if uncertain then just get the test done. Good luck man.
 

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Just posting these ups for open critique,
Gotta call and schedule a video conference with one their doctors on monday...didn't give myself the time to do it this week because of the new puppz 🥰🥰

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Just posting these ups for open critique,
Gotta call and schedule a video conference with one their doctors on monday...didn't give myself the time to do it this week because of the new puppz 🥰🥰

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Mean corpuscular biomarkers, combined with high RDW imply you may have some iron deficiency going on. Surprisingly those values are a bitch to get back in check, and take some time. I fought them for quite some time until I learned how to get enough bio available iron into my diet.

I notice my values sink more when I'm blasting something. I suspect it has to do with increased RBC production that occurs from increased hormones in the system; as my RBC tends to go up when those values go down. Coincidentally it seems to be prevalent during blast and I've seen the same in other people's blood work. It is possible to avoid entirely, even when on a blast, through diet alone. I've been able to get mine under control with diet, and others I've given very general guidance to have controlled theirs as well.

While there can be a performance impact, and even an impact to IGF levels, for me the effect it has on RDW is most concerning. High RDW is associated with increases in cardiovascular morbidity. This doesn't mean you're going to die tomorrow, but it's something you should try to get a handle on before it gets out of control.

Combine this with your cholesterol; which is pretty crappy (just being honest). Part of this could be other compounds you're taking (not sure what you're cycling), but I've seen your diet juice. Your diet is shit 😂. I'm sure we're all aware that poor lipid values is no bueno for arteries or the heart.

Summary; if general health is of interest then eat better, make sure you get more bio available iron, and maybe add a bit of cardio into your life. It's easier to get things under control now than when you're older and set in your ways.

There are those who I'm sure will chime in and say I'm wrong, and that those biomarkers don't mean anything because it could be genetic. To which I ask you, why take a chance and shrug your shoulders at the values you see... instead of at least making a base line effort to control it? 🤷‍♂️

Good luck!
 

JuiceTrain

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Appreciate the input as always @Send0
More notes to jot down 🤟🏾

Question....does fasting/not fasting drastically affect these numbers?

It says fasted but I'm 100% certain I ate beforehand on these test....usually it's a 50/50 toss up lol

And I seen your thread before about cooking in a cast iron pot to increase iron, I'll bring that up with the doc
 
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Just posting these ups for open critique,
Gotta call and schedule a video conference with one their doctors on monday...didn't give myself the time to do it this week because of the new puppz 🥰🥰

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Sickle cell anemia. You hemoglobin values are down. Your RDW is high. Those are indications of sickle cell. Schedule a visit with your doctor to go over that page of your blood work.
 

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Sickle cell anemia. You hemoglobin values are down. Your RDW is high. Those are indications of sickle cell. Schedule a visit with your doctor to go over that page of your blood work.
It's more likely to be low iron or ferritin. I would put a years paycheck on him being in the low end of the range for one or both. Everytime this has come up, it's been low iron. It also results in low hemoglobin despite having higher RBC.



I agree he should review with his doctor.
 

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Appreciate the input as always @Send0
More notes to jot down 🤟🏾

Question....does fasting/not fasting drastically affect these numbers?

It says fasted but I'm 100% certain I ate beforehand on these test....usually it's a 50/50 toss up lol

And I seen your thread before about cooking in a cast iron pot to increase iron, I'll bring that up with the doc
It wouldn't effect MC biomarkers, or RDW. It would effect things like glucose and triglycerides. LDL is also effected, but returns to "normal" values much faster compared to something like triglycerides, and is not AS sensitive to being fasted compared to something like glucose or triglycerides.

Have your doc run a ferritin and iron level test. If you're in the bottom of the range, and he says don't worry about it... then I feel the need to emphasize that bottom of the range for those biomarkers is not acceptable. You want to be right about in the middle.
 
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It's more likely to be low iron or ferritin. I would put a years paycheck on him being in the low end of the range for one or both. Everytime this has come up, it's been low iron. It also results in low hemoglobin despite having higher RBC.



I agree he should review with his doctor.
Low iron could be because he has sickle cell anemia. Sickle cell symptoms are exactly what he describes. It’s enough of a concern that the NCAA has a requirement this year that all athletes be tested for it, regardless of race. It’s an easy test to get.

He’s on a blast and yet he still has low hemocrit and hemoglobin values. Juice likely never has to donate blood (lol, unless he just did and that is the issue).

 
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Low iron could be because he has sickle cell anemia. Sickle cell symptoms are exactly what he describes. It’s enough of a concern that the NCAA has a requirement this year that all athletes be tested for it, regardless of race. It’s an easy test to get.

He’s on a blast and yet he still has low hemocrit and hemoglobin values. Juice likely never has to donate blood (lol, unless he just did and that is the issue).
You're right, it's easy to test for. They even test for this in middle school in the US, at least they used to.

I had very similar blood work on blast, as have others on the forum, and it was addressed by making iron more bioavailable in diet.

Here is mine mid blast, and again 4-5 months later (takes a long time to build up iron stores). The first test I ordered all the panels myself, and the second time my doctor did my yearly physical and I ordered the iron test separately. I only have ferritin for the first time; it measured at 15ng/ml, and the range is 38 - 380. Didn't bother getting ferritin the second time.

I reduced my iron intake after getting the results seen in the second set of tests.

Again, you are correct in that he should review with his doctor for next steps/additional tests. It could be iron deficiency or it could be something more serious.
 

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@JuiceTrain sickle cell is also associated with episodes of pretty bad pain that might feel like it's coming from bone or muscle. I have two friends with sickle cell, and they say it's not like a muscle strain or DOMs. It's much more severe and often is debilitating. If you have this, then definitely mention it to your doctor. The good news is that sickle cell is not as common as people believe. The CDC currently estimates 100,000 Americans have it.

In this case it's a good thing that we can't look at a single biomarker and say "ah ha". It's important to combine it with other biomarkers, and even then this is simply a diagnostic tool to determine if more in depth testing is warranted.

If anyone wants to speculate about potentially more alarming health issues then technically in addition to common iron deficiency, high RDW could also indicate cancer, Crohn's, diabetes, HIV, thalassemia, or other blood disorders. This is one reason why we can't look at any biomarker in isolation. The doctor will determine what condition, if any, that you have. More often than not the simplest answer matching symptoms or values seen in blood work is the correct answer.

Good luck man.
 

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