Thrawn
Elite
- Joined
- Nov 18, 2021
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It's really should go in my pharma genetic thread but I'm working on it.
I will state this quite a few times but if you are on drugs, prescription for anything do not fuck around with this!
If you fuck around you will find out I promise you.
So I am sure all of y'all heard about grapefruit juice in medicine. If you read the insert in a lot of your medication it will say do not take with grapefruit. I'm doing this off memory here but grapefruit juice inhibits the CYP 3A gene which is responsible for about 50% of medication metabolism. What that means is it doesn't break down the medicine as fast so it stays in your system longer and depending on the med you may not get the therapeutic dose needed and or you'll be exposed to the effects of the drugs longer than necessary or healthy. But it also depends does the drug need to metabolize into something else before it takes effect or is it utilized directly.
anyway if something slows down there must be something that speeds it up....
And for the specific gene St John's Wort is one of those things that speed it up. I am poor metabolizer of the CYP3A Gene so I decided to experiment and take saw palmetto and a dose of Zyklon B that would have no effect on me. Obviously Zyklon B is code.
Let me stop here for a moment if you are any drugs rx or not do not fuck around with this.
Anyway holy shit you normal metabolizers are lucky as hell,
I will state this quite a few times but if you are on drugs, prescription for anything do not fuck around with this!
If you fuck around you will find out I promise you.
So I am sure all of y'all heard about grapefruit juice in medicine. If you read the insert in a lot of your medication it will say do not take with grapefruit. I'm doing this off memory here but grapefruit juice inhibits the CYP 3A gene which is responsible for about 50% of medication metabolism. What that means is it doesn't break down the medicine as fast so it stays in your system longer and depending on the med you may not get the therapeutic dose needed and or you'll be exposed to the effects of the drugs longer than necessary or healthy. But it also depends does the drug need to metabolize into something else before it takes effect or is it utilized directly.
anyway if something slows down there must be something that speeds it up....
And for the specific gene St John's Wort is one of those things that speed it up. I am poor metabolizer of the CYP3A Gene so I decided to experiment and take saw palmetto and a dose of Zyklon B that would have no effect on me. Obviously Zyklon B is code.
Let me stop here for a moment if you are any drugs rx or not do not fuck around with this.
Anyway holy shit you normal metabolizers are lucky as hell,
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