Ozempic

Joined
Dec 15, 2022
Messages
11
Reaction score
3
Points
3
I immediately started with a dosage of 0.5 mg. The doctor approved this step. I lost 5 kg in the first week! Side effects play a big role in the speed of weight loss. I often feel nauseous, my appetite has practically disappeared. I eat 1 time a day and don't eat much. Now I can have one cup of coffee with a sandwich and everything is fine. Maybe later the weight loss will slow down? I really hope so.
 

Send0

Taskmaster (Moderator)
Joined
Oct 28, 2020
Messages
13,322
Reaction score
23,060
Points
383
I immediately started with a dosage of 0.5 mg. The doctor approved this step. I lost 5 kg in the first week! Side effects play a big role in the speed of weight loss. I often feel nauseous, my appetite has practically disappeared. I eat 1 time a day and don't eat much. Now I can have one cup of coffee with a sandwich and everything is fine. Maybe later the weight loss will slow down? I really hope so.
Sounds like you should have started with an even smaller dose and titrated your way up every 4 weeks.
 

Kraken

Senior Member
Joined
Dec 3, 2020
Messages
2,003
Reaction score
1,821
Points
113
It's hard to explain but closing your mouth and putting the fork down isn't allways the case. If you know , you know...

It's ALMOST worse than being an alcoholic in recovery. The alcoholic can't stop after that first drink, but they can fight like hell to not have that first drink. People who tend to over eat and need to control their intake still have to take that first bite. It's easier to stop eating than it is for an alcoholic to stop drinking, but that does not mean it's easy.

I immediately started with a dosage of 0.5 mg. The doctor approved this step. I lost 5 kg in the first week! Side effects play a big role in the speed of weight loss. I often feel nauseous, my appetite has practically disappeared. I eat 1 time a day and don't eat much. Now I can have one cup of coffee with a sandwich and everything is fine. Maybe later the weight loss will slow down? I really hope so.

So when people are eating much less due to artificially reduced appetite, are they losing a lot of muscle? I would think a person would have to be careful to eat a lot of protein and do some lifting to maintain muscle and drop mostly fat. I suspect most people who use a drug like this, don't do that.
 

transcend2007

Elite
SI Founding Member
Joined
Aug 20, 2012
Messages
4,195
Reaction score
3,406
Points
193
So when people are eating much less due to artificially reduced appetite, are they losing a lot of muscle? I would think a person would have to be careful to eat a lot of protein and do some lifting to maintain muscle and drop mostly fat. I suspect most people who use a drug like this, don't do that.
This ^^^ Dr Attia has tracked via dexa scan exactly this issue ... and yes lean mass is lost because people already struggle getting adequate protein on a normal diet when restricted it basically reduces further and lean mass is lost ...

The other issue is that some people who never feel hungry increased alcohol or other empty calorie foods due to just never being hungry ...

Worst of all nearly all people who stopped taking the drug regained the all their weight due to not learning any health lifestyle strategies such as exercise or eating better ...

Like other appetite suppressants they work well while taken but create an unhealthy rebound effect when stopped ...

The other lesson learned is for people who say they JUST CANNOT LOSE WEIGHT any other way due to insulin resistance or other factor ... the fact is they do lose weight when the stop overeating (through suppressed appetite) ... which in fact proves they actually can lose weight ... by restricting calories ... there are NO OTHER MAGIC BULLETS that people have attempted to state ... Semaglutides simply make it possible to restrict calories ... plus the mind is a powerful thing ... when people believe they achieve ... unfortunately even that fact is negated once they come off the medication because they did not learn skills required maintain their result which is the most unfortunate part ...
 
  • Like
Reactions: A1c

snake

Veteran
Joined
Jan 29, 2014
Messages
12,728
Reaction score
20,534
Points
383
I immediately started with a dosage of 0.5 mg. The doctor approved this step. I lost 5 kg in the first week! Side effects play a big role in the speed of weight loss. I often feel nauseous, my appetite has practically disappeared. I eat 1 time a day and don't eat much. Now I can have one cup of coffee with a sandwich and everything is fine. Maybe later the weight loss will slow down? I really hope so.
That's like eating 5,000 cal less each day. Of course, some is water but damn help me out here. How many cals were you consuming in a normal day?

I'm not judging you, just trying to wrap my mind around 10 lbs in a week.
 

Kraken

Senior Member
Joined
Dec 3, 2020
Messages
2,003
Reaction score
1,821
Points
113
That's like eating 5,000 cal less each day. Of course, some is water but damn help me out here. How many cals were you consuming in a normal day?

I'm not judging you, just trying to wrap my mind around 10 lbs in a week.

Well that was the first week. As you said, water is lost. If someone is particularly big (I don't know if this guy is or not) then very rapid weight loss is possible, at least for a time.
 

snake

Veteran
Joined
Jan 29, 2014
Messages
12,728
Reaction score
20,534
Points
383
Well that was the first week. As you said, water is lost. If someone is particularly big (I don't know if this guy is or not) then very rapid weight loss is possible, at least for a time.
Thanks brother! I'm just trying to wrap my mind around this. I never had a weight problem so it's far from home for me.
 

Send0

Taskmaster (Moderator)
Joined
Oct 28, 2020
Messages
13,322
Reaction score
23,060
Points
383
This ^^^ Dr Attia has tracked via dexa scan exactly this issue ... and yes lean mass is lost because people already struggle getting adequate protein on a normal diet when restricted it basically reduces further and lean mass is lost ...
Was he tracking normies? Or people who are serious about fitness or body building?

Because I'm pretty sure that people who are serious would get their protein in no matter what.

I constantly felt bloated or uncomfortably full during my short 3 month experiment with semaglutide. That did not stop me from making sure I got all my protein in. It really wasn't too difficult, even if I didn't feel like doing it at times. I sucked it up and did it anyway. 🤷‍♂️
 
Joined
Oct 5, 2023
Messages
41
Reaction score
31
Points
8
It seems to work MUCH better in gen pop people than fit/healthy people, but it can still be a gamechanger nonetheless. I'm guessing that gen pop/obese people have appetites that are so disregulated from what their baseline should be, so that could account for why it seems to work better in those populations. When your appetite is already where it "should" be, it's harder to disrupt that homeostasis, even with pharmacology.
 
Joined
Mar 29, 2024
Messages
12
Reaction score
0
Points
1
I've used semaglutide twice now. It's VERY effective. Especially when combined with DNP (which can give you crazy carb cravings).
 
Joined
Mar 20, 2024
Messages
17
Reaction score
0
Points
1
So, doing a bunch of googling it seems there are weight loss clinics pushing this, and similar, stuff. Apparently the clinical studies talk about losing 5% of body weight in a year. So if I'm 160 pounds, I can expect to lose a whopping 8 pounds after an entire year? People should be able to lose 8 pounds in 2 to 4 weeks on any normal, non drug related, diet.

I don't see the attraction, especially at the price point... Surly I'm missing something?
what are you looking for?
 
Joined
Sep 16, 2024
Messages
9
Reaction score
0
Points
1
The sole most effective thing to lose weight still is a calorie deficit. All these medications will do more harm than good.
 

Attachments

eazy

Elite
Joined
Mar 23, 2021
Messages
5,140
Reaction score
14,401
Points
333
The sole most effective thing to lose weight still is a calorie deficit. All these medications will do more harm than good.
what does the attachment say?
 

eazy

Elite
Joined
Mar 23, 2021
Messages
5,140
Reaction score
14,401
Points
333
It says "What is calorie deficit", just an informational pamphlet.
what led you to believe anyone here needed that pamphlet?

why not copy and paste the information into your post?
 

GreatGunz

Elite
Joined
Dec 1, 2013
Messages
1,086
Reaction score
720
Points
83
Well my wife WAS a big girl…….
She is down 60lbs in a year using epic.
It smashes ur appetite and if u try to crame food you’ll puke.
 
Joined
Sep 16, 2024
Messages
9
Reaction score
0
Points
1
Well my wife WAS a big girl…….
She is down 60lbs in a year using epic.
It smashes ur appetite and if u try to crame food you’ll puke.
Another way is to drink lots of warm water. It also acts as appetite supressos incredibly well. Nobody just takes it seriously as they think they are so grown-up they need serious medications for grown-ups.

I lost about 40kg when drank water. The only thing is that you need to know how much you really need. Because if you drink more than you need you'll get tired super quickly. Or drinking warm water. Because in the beginning (especially) it's very unpleasant feeling and easy to drop it.

If you drink less than needed, you won't see an effect. There are daily water intake calculator, which will tell you how much you need. Calculate, because there are several parameters, like weight, climate, gender, etc..
"Easy, but not easier" as Einstein or whoever said that, so still need a miniscule amount of effort..
 
Top