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Taskmaster (Moderator)
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that article is kind of misleading, and doesn't give full context of the background, health issues, activity level, etc of the men who had those levels. It focused specifically on men who had chronic heart failure; not exactly a scenario representative of most men."The men in the balanced quintile-with the fewest deaths-had serum estradiol levels between 21.80 and 30.11 pg/mL.'
Importance of Testosterone and Estrogen in Men - Life Extension
Massachusetts General Hospital consistently ranks as one of the world's top medical facilities. It conducts the largest hospital-based research program in the United States.www.lifeextension.com
Also estradiol shouldn't be looked at in isolation, total and free testosterone needs to be looked at as it relates to estradiol as well.
There are lots of biases, as well as specificities, in that article required to make it have value even to a small demographic of men it seems to be targeting.